Investigating processes in the in vitro cell cultures are aimed to follow the proliferation and life of the cells in living organism.
THE VIRTUAL SKIN MODEL
The skin, one of the biggest organs of our organism, is formed by cells displaying specialised functions, including epidermal cells (keratinocytes), dermis cells (fibroblasts), pigment cells (melanocytes), fat cells (adipocytes). Any type of cells can be isolated and kept alive under laboratory conditions. Cell co-cultures are developed, e.g. epidermal cells with pigment cells, as well as epidermis and full-thickness skin models. Therefore, three-tier 3D models are used for cosmetic safety testing.
In cosmetology, cell cultures are an excellent material for advanced research on active substances. They allow for safe determination of optimal operating doses for new, never used ingredients. Cell research allows for carrying out a series of studies to explain the mechanisms of action of active ingredients contained in cosmetics. They allow for observation of skin aging processes, the skin’s ability to fight-off harmful environmental factors or restore after damage.